The case of a human immunodeficiency virus (HIV) and hepatitis C virus (HCV)-coinfected patient with a past medical history of deep venous thrombosis is presented. A liver biopsy, performed for unexpected finding of portal hypertension, showed vascular lesions presenting as nodular regenerative hyperplasia. Vascular liver diseases seem to be emerging as a new cause of chronic liver disease in HIV-infected patients under combined antiretroviral therapy. The syndrome of HIV-associated liver vasculopathy is discussed.
Key words: nodular regenerative hyperplasia; portal hypertension; HIV infection.